There is still hope.
Spravato (esketamine) for treatment-resistant depression — over 30,000 treatments administered across our 4 NJ locations, with nearly all insurance accepted.
Treatments administered
NJ locations
Typical copay per session
Why Patients Choose Our Spravato Program
Real experience, real access, and integrated care — not a one-and-done treatment mill.
30,000+ Treatments
Deep, practical experience with induction, dosing, and side-effect management — not a provider's first few dozen sessions.
Nearly All Insurance Accepted
We handle prior authorization for you. Authorization is typically approved within 24-48 hours.
$0–$40 Typical Copay
From $0 for Medicaid patients up to $40 for most other plans. We also have extensive experience helping patients enroll in the manufacturer's patient assistance program when cost is still a barrier.
4 Convenient NJ Locations
Bridgewater, Nutley, Hoboken and Morristown — a treatment center within reach across Central and Northern New Jersey.
What Is Spravato Treatment?
Spravato (esketamine) is an FDA-approved nasal spray for adults with treatment-resistant depression who haven't found relief from other antidepressants. If you've tried two or more medications without success, Spravato offers a new path forward.
Unlike traditional antidepressants that can take weeks to work, many patients experience improvement within hours or days. Spravato works differently than other depression medications by targeting NMDA receptors in the brain, helping restore neural connections that depression has weakened.
Treatment takes place in our comfortable, private treatment spaces. Each session lasts about 2 hours including monitoring time. You'll self-administer the nasal spray under our supervision, then rest while we monitor your response.
What makes our program different:
- 30,000+ treatments administered across our NJ locations
- Nearly all insurance accepted, with a dedicated team handling authorization paperwork
- Can be paired with therapeutic counseling and psychiatric medication management so your care stays coordinated under one team
- Regular reassessment throughout treatment, not just at intake, to confirm the plan is actually working
- Same providers throughout your treatment — you're not passed between different doctors
Who Can Benefit From Spravato?
Treatment-Resistant Depression
You've tried at least two different antidepressants without adequate relief.
Major Depressive Disorder
Your depression significantly interferes with daily life, work, relationships, or your ability to function.
Persistent Symptoms
Despite medication and therapy, you still struggle with hopelessness, low energy, or loss of interest in activities.
Acute Suicidal Thoughts
Spravato can be used for adults with major depressive disorder experiencing acute suicidal ideation or behavior.
If you're in crisis right now, call or text 988 (Suicide & Crisis Lifeline) or go to your nearest emergency room.
You haven't failed. Your treatments have failed you.
Confidential evaluations, in person or by telemedicine, typically available within 24-48 hours.
What to Expect at Your Spravato Appointment
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Initial Consultation (30–45 minutes)
We review your depression history and previous treatments to determine if Spravato is right for you, and handle insurance verification and pre-authorization. Available in person or by telemedicine.
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Treatment Session (about 2 hours)
You'll arrive at our comfortable treatment room and self-administer the nasal spray under our supervision, then rest while we monitor your response.
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Monitored Rest Period
You'll rest in our private treatment space while we track your vital signs and response. Many patients describe feeling relaxed; you can listen to music or simply rest.
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Going Home
Once your provider confirms you're stable, you can go home — you'll need someone to drive you. Most patients return to normal activities the same day or next morning.
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Ongoing Reassessment
Initially twice a week, then once weekly, then monthly for maintenance — with regular check-ins on your progress, not just a fixed schedule regardless of how you're responding.
Important to know:
- Bring someone to drive you home — you cannot drive for 24 hours after treatment
- Avoid eating for 2 hours before your appointment
- Continue taking your regular antidepressant medication as prescribed
Common Questions About Spravato
How many Spravato treatments has MyPremierMD administered?
Over 30,000 Spravato treatments across our NJ locations, giving our team deep, practical experience with induction, dosing, and side-effect management.
Does insurance cover Spravato?
We accept nearly all insurance plans, including Medicare and Medicaid, and our team handles prior authorization for you. Authorization typically comes back within 24-48 hours. Most patients pay between $0 (Medicaid) and $40 per session, and we have extensive experience helping patients enroll in the manufacturer's patient assistance program if cost is still a barrier.
Can I combine Spravato with therapy or medication management?
Yes. Spravato works alongside your existing antidepressant, and many patients pair it with our therapeutic counseling and psychiatric medication management services so all of your mental health care stays coordinated under one team.
How is my progress monitored during treatment?
We reassess your symptoms at regular intervals throughout your treatment course, not just at intake, adjusting your schedule and coordinating with any therapy or medication management you're also receiving.
How quickly can I be seen for a Spravato evaluation?
Initial evaluations are available in person or by telemedicine, typically within 24-48 hours of calling.
Why do I have to stay for two hours and have someone drive me?
Because it's federally required, not because we're being cautious for the sake of it. Spravato is only available through a restricted program (a REMS) that requires it be self-administered at a certified treatment center and that you're monitored on site for at least two hours afterward, with blood pressure checked along the way. You can't drive for the rest of the day. It's the same reason Spravato isn't a prescription you can pick up at a pharmacy and use at home — and it's exactly what makes a practice with 30,000+ treatments behind it worth choosing.
What does it actually feel like, and what are the side effects?
Most patients describe a floaty, detached, slightly dreamlike feeling during the session that fades well before they go home. The common side effects are dissociation, dizziness, nausea, a temporary rise in blood pressure, sedation, and an odd taste — and they generally get milder over a course of treatment as your body adapts. We monitor for all of it in the room. If nausea is an issue for you, that's manageable, and it's part of why we ask you not to eat for two hours beforehand.
How soon might I notice a difference?
Faster than a conventional antidepressant, which is much of the point — some patients notice a shift within the first week or two, where an SSRI typically needs four to six weeks. That said, it isn't universal and it isn't instant for everyone. Treatment starts at twice weekly for the first month, then moves to weekly, then to a maintenance interval based on how you're actually doing. We reassess your symptoms throughout rather than running you through a fixed schedule and hoping.
Spravato Across 4 NJ Locations
Care that runs alongside Spravato
Spravato works best as part of a plan, not on its own. All of this happens in the same practice, with the same chart.
Depression Care
The full picture of how we treat depression — what's tried before Spravato, and what happens if it isn't the right fit for you.
Learn moreMental Health Care
Psychiatric medication management and coordinated counseling from a team that includes a dedicated psychiatric PA.
Learn moreThyroid Testing
Untreated thyroid disease mimics and worsens depression. It gets checked here rather than assumed away.
Learn moreContact MyPremierMD Today
We'll reach out within 24 hours to answer your questions and help you schedule an appointment.